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Search Results for " ras/erk activation "

5

Compounds

Cat No. Product Name Synonyms Targets
T20759 XRP44X XRP-44-X,XRP 44X,XRP-44X,XRP 44 X Ras
XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.
TN2114 Pseudoginsenoside Rh2 ERK , Raf , p53
Pseudoginsenoside Rh2 has cytotoxicity, it induces mitochondrial apoptosis in A549 cells and is responsible for excessive activation of the Ras/Raf/ERK/p53 pathway. (20Z) -Pseudoginsenoside Rh2 and (20E)-Pseudoginsenosid...
T69195 UC-857993
UC-857993, a selective SOS1-Ras inhibitor (Kd=14.7 μM, His6-SOS1cat), effectively suppresses catalytic activity. In addition to inhibiting ERK and Ras activation, it also hampers the growth of mouse embryonic fibroblasts...
T37422 Ras Inhibitory Peptide
Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to t...
T71163 Pimasertib HCl
Pimasertib HCl is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity. Pimasertib selectively binds to and inhibits the activity of MEK1/2, preventing the acti...
TargetMol